David Largaespada Headshot

Professor, Departments of Genetics,
Cell Biology and Development
University of Minnesota


David A. Largaespada, PhD is an authority on mouse genetics, gene modification, cancer genes, and disease models. His lab specializes in cancer functional genomics using in vivo transposon mutagenesis and targeted nucleases. Current projects are focused on sarcomas, brain tumors, hepatocellular carcinoma, and Neurofibromatosis Type 1 syndrome. He is currently a Full Professor in the Department of Pediatrics and the Department of Genetics, Cell Biology and Development at the University of Minnesota. He is the Associate Director for Basic Research in the Masonic Cancer Center at University of Minnesota. Dr. Largaespada currently holds the Hedberg Family/Children’s Cancer Research Fund Endowed Chair in Brain Tumor Research. Dr. Largaespada was awarded the University of Minnesota McKnight Land-Grant Professorship in 2000 and the American Cancer Society Research Professor Award in 2013. He has published over 170 scientific articles, many in high impact journals such as Science, Nature and Nature Genetics. Dr. Largaespada has co-founded three biotechnology companies.